CIMmultus™ SO3-1 Advanced Composite Column (Sulfonyl) (Pores 2 um)

CIMmultus™ stands for:

• Convective mass transfer, reduced backpressure, and minimal sample clogging
• Fast product isolation and concentration of diluted samples
• Efficient removal of high molecular mass impurities in polishing steps

CIMmultus™ SO3-1 mL is an improved monolithic column with 2 um pore size and a column volume of 1 mL. It is packed into an innovative epoxy-based housing and is supplied ready to use. CIMmultus™ SO3-1 mL is intended for initial screening, method development, and lab scale purifications. SO3 (sulfate) is a strong cation exchange group that selectively binds molecules with a predominant positive charge over a working pH range of 2-13. SO3 is a versatile chemistry and has proven to be excellent for:

• Concentration of viruses, VLPs, and large proteins that bind to the ion exchanger on the basis of their positive charge.
• Sound and efficient removal of aggregates in mAb production; operate it in flow-through mode during the polishing step.